Most freight haulers are not hiring now, but to answer your question, it's hard to get on with a freight hauler after otr. I have not understood it but was told one time that otr drivers are set in their ways, a lot are lazy, and most don't have customer service skills. Not my words driver, just what a terminal manager has told me. It would be easier in a good economy though.
If you decide to try, I wish you all the luck. In my opinion, ltl is where it is at. Good pay, benifits, and home. Although p&d your home late a lot, linehaul your gone at night. Either way if you have kids at home you may not see them much, but being gone a couple weeks at a time is much worse. Again, good luck.
BTW, terminal manager was not with this company, but I think their thoughts are about the same at all ltl companies.